UBASH3A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530713-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA530713 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
UBASH3A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
UBASH3A
Gene Alias
5830413C03Rik; C330001M22; Cbl-interacting protein 4; CLIP4; STS2; Sts-2; Suppressor of T-cell receptor signaling 2; T-cell ubiquitin ligand 1; T-cell ubiquitin ligand protein; TULA; TULA1; TULA-1; Ubash3a; ubiquitin associated and SH3 domain containing A; ubiquitin associated and SH3 domain containing, A; ubiquitin-associated and SH3 domain-containing protein A
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
53347
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.8 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P57075
Gene Symbols
UBASH3A
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 40 and 316 of Human UBASH3A
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: K562
- Predicted reactivity: Mouse (86%), Dog (89%), Bovine (87%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- TULA (T cell ubiquitin ligand, UBASH3A, ubiquitin associated and SH3 domain containing A), STS-2 or CLIP4, is a 661 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one SH3 domain and one UBA domain
- Expressed at high levels in thymus, bone marrow, spleen and peripheral blood leukocytes, TULA exists as either a homodimer or a homo-oligomer that interferes with the degradation of receptor-type tyrosine kinases and promotes the accumulation of activated receptors on the cell surface
- Additionally, TULA is part of an EGFR- and Cbl-containing complex that interacts with ubiquitinated proteins
- The gene encoding TULA, which maps to human chromosome 21, may be involved in the pathogenesis of type I diabetes
- Multiple isoforms of TULA are produced due to alternative splicing events.