PIPA532019

TBC1D22A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA532019-Each-of-1 In Stock ₹ 46,502.50

PIPA532019 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TBC1D22A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TBC1D22A

Gene Alias

BC023106; C22orf4; D15Ertd781e; HSC79E021; putative GTPase activator; RGD1306588; TBC1 domain family member 22A; TBC1 domain family, member 22a; TBC1D22A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25771

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q8WUA7

Gene Symbols

TBC1D22A

Immunogen

Recombinant fragment corresponding to a region within amino acids 11 and 315 of Human TBC1D22A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A431, HeLa, HepG2
  • Predicted reactivity: Mouse (85%), Bovine (82%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members
  • Multiple isoforms of TBC1D22A exist due to alternative splicing events
  • The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome
  • Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia
  • Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.