PIPA532111

MRVI1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA532111-Each-of-1 In Stock ₹ 47,036.50

PIPA532111 - Each of 1

₹ 47,036.50

In Stock

Quantity

1

Base Price: ₹ 47,036.50

GST (18%): ₹ 8,466.57

Total Price: ₹ 55,503.07

Antigen

MRVI1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MRVI1

Gene Alias

BB115629; inositol 1,4,5-triphosphate receptor associated 1; inositol 1,4,5-triphosphate receptor associated 1; protein MRVI1; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate; inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; IP3 receptor associated cGMP kinase substrate; IP3 receptor associated cGMP kinase substrate A; IP3 receptor associated cGMP kinase substrate B; IP3R-associated cGMP kinase substrate; IRAG; IRAG1; JAW1L; JAW1-related protein MRVI1; MRV integration site 1; MRVI1; murine retrovirus integration site 1 homolog; murine retrovirus integration site 1 protein; Protein MRVI1; retroviral integration site 1; Ris1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10335

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9Y6F6

Gene Symbols

MRVI1

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 404 and 547 of Human MRVI1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: MCF-7
  • Predicted reactivity: Rat (86%), Bovine (88%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV)
  • The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is downregulated during lymphoid differentiation
  • Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene
  • Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, few of which initiate translation at a non-AUG (CUG) start site.