PIPA532330
CD68 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA532330-Each-of-1 | In Stock | ₹ 47,036.50 |
PIPA532330 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
CD68
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cd68
Gene Alias
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
968
Content And Storage
4° C, do not freeze
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.18 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.
P34810
Gene Symbols
Cd68
Immunogen
Synthetic peptide near the C-terminus of human CD68 protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
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Description
- Heat-mediated antigen retrieval is recommended prior to staining, using an EDTA buffer for 10 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
- A suggested positive control is tonsil or lung tissue
- CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes
- Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions
- CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma
- Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.