STAT6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA532603-Each-of-1 | In Stock | ₹ 42,853.50 |
PIPA532603 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,853.50
GST (18%): ₹ 7,713.63
Total Price: ₹ 50,567.13
Antigen
STAT6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT6
Gene Alias
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6778
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ChIP Assay, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.28 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.
P42226
Gene Symbols
STAT6
Immunogen
Synthetic peptide derived from C-terminus of human STAT6.
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with canine, mouse, porcine, rabbit based on sequence homology
- Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
- A suggested positive control is placenta or tonsil tissue
- STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13
- (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation
- STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta
- STAT6 is critically involved in Th2 immune response
- STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.