CCR8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA532699-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA532699 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
CCR8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CCR8
Gene Alias
C-C; CC chemokine receptor 8; CC chemokine receptor CHEMR1; C-C chemokine receptor type 8; C-C CKR-8; C-C motif chemokine receptor 8; CC-chemokine receptor chemr1; CC-CKR-8; CCR8; CCR-8; cd198; CDw198; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; chemokine receptor-like 1; CKR-8; CKRL1; CKR-L1; Cmkbr8; CMKBRL2; CY6; GPRCY6; GPR-CY6; mCCR8; MGC129966; MGC129973; TER1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1237
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P51685
Gene Symbols
CCR8
Immunogen
Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human CCR8.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%); Gibbon, Marmoset (95%); Bovine, Horse (84%)
- For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen
- CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors
- Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites
- This receptor protein preferentially expresses in the thymus
- I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP1 beta) have been identified as ligands of this receptor
- Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis
- More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues
- This gene is located at the chemokine receptor gene cluster region
- CCR8 expression has been reported in spleen and thymus, natural-killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes.