PIPA533396

CCR3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533396-Each-of-1 In Stock ₹ 46,502.50

PIPA533396 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CCR3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CCR3

Gene Alias

b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; C-C motif chemokine receptor 3; CC-CKR3; CC-CKR-3; Ccr3; CCR-3; CD193; chemokine (C-C motif) receptor 3; chemokine (C-C) receptor 1,-like 2; chemokine (C-C) receptor 3; CKR3; Cmkbr1l2; CMKBR3; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; Macrophage inflammatory protein 1-alpha receptor-like 2; MGC102841; MIP-1 alpha RL2; MIP-1 alphaRL2; probable C-C chemokine receptor type 3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1232

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P51677

Gene Symbols

CCR3

Immunogen

Synthetic 16 amino acid peptide from C-terminus of human CCR3.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon (94%) Marmoset, Dog, Rabbit (88%) Mouse, Bovine, Hamster, Horse (81%)
  • CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta
  • CCR3 trasnduces a signal by increasing the intracellular calcium ions level
  • It also serves as an alternative co-receptor with CD4 for HIV-1 infection
  • Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection
  • Chemokines activate leukocytes by binding to G protein coupled receptors
  • The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines.