PIPA533363

Bestrophin 2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533363-Each-of-1 In Stock ₹ 46,502.50

PIPA533363 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Bestrophin 2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BEST2

Gene Alias

BEST2; bestrophin 2; bestrophin-2; Hbest2; vitelliform macular dystrophy 2-like 1; vitelliform macular dystrophy 2-like protein 1; VMD2L1; VMD2L-1; VMD2-like gene 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100856525, 54831

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

0.9 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

Q8NFU1

Gene Symbols

BEST2

Immunogen

Synthetic 15 amino acid peptide from internal region of human BEST2 / Bestrophin-2.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Dog (100%) Mouse, Hamster, Panda, Bovine (93%) Opossum (87%)
  • Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate
  • The Best2 gene is a member of the bestrophin gene family of anion channels
  • Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends
  • Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif
  • Mutation in the Best2 gene is associated with vitelliform macular dystrophy
  • The Best2 gene is mainly expressed in the retinal pigment epithelium and colon
  • Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.