PTGER2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA533512-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA533512 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PTGER2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTGER2
Gene Alias
EP2; EP2 receptor; PGE receptor EP2 subtype; PGE receptor, EP2 subtype; PGE2 receptor EP2 subtype; Pge2-r ep2; prostaglandin E receptor 2; prostaglandin E receptor 2 (EP2 subtype); prostaglandin E receptor 2 (subtype EP2); prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostaglandin E receptor EP2 subtype; prostaglandin E receptor subtype EP2; prostaglandin E2 receptor EP2; prostaglandin E2 receptor EP2 subtype; prostaglandin E2 receptor EP2 subtype pseudogene; prostaglandin E2 receptor type 2; prostanoid EP2 receptor; Ptger2; Ptgerep2; Ptger-ep2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5732
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P43116
Gene Symbols
PTGER2
Immunogen
Synthetic 16 amino acid peptide from internal region of human EP2.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey, Marmoset, Mouse, Rat, Hamster (94%); Bat, Dog, Pig (88%); Gibbon, Panda, Horse (81%)
- For IHC(P), use proteinase K antigen retrieval
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen
- Prostaglandins are produced by the metabolism of arachidonic acid
- Prostaglandin E2 is one of the five physiologically significant prostanoids known
- Its wide spectrum of physiologic and pharmacologic effects in various tissues is mediated through binding to the Prostaglandin E2 receptors (EP1, EP2, EP3 & EP4)
- These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle
- It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation
- PGE-2 signals through a family of G-protein coupled receptors known as EP receptors
- There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4
- EP2 receptors are 358 amino acid proteins with a short third intracellular loop
- EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization
- The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue
- These receptors are mainly localized in lung and placental tissues and in smooth muscle.