GPR68 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA533756-Each-of-1 | In Stock | ₹ 48,015.50 |
PIPA533756 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,015.50
GST (18%): ₹ 8,642.79
Total Price: ₹ 56,658.29
Antigen
GPR68
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GPR68
Gene Alias
BB131428; Brgr1; Brgrb; G protein-coupled receptor 68; GPR12A; Gpr68; G-protein coupled receptor 68; Ogr1; OGR-1; ovarian cancer G protein-coupled receptor, 1; ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100053071, 100153615, 100752950, 103351698, 238377, 281799, 314386, 8111
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
O46685, Q15743, Q8BFQ3
Gene Symbols
GPR68
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GPR68.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Bovine, Equine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Rabbit, Pig (100%)
- GPR68 (also known as OGR1 - ovarian cancer G-protein coupled receptor 1) is a proton-sensing receptor involved in pH homeostasis
- It represents an osteoblastic pH sensor regulating the cell-mediated response to acidosis in bone
- GPR68 mediates its action by association with G proteins that stimulate inositol phosphate (IP) production or CA2+ mobilization
- The receptor is almost silent at pH 7.8 but fully activated at pH 6.8
- Also found to serve as a tumor suppressor in prostate cancer
- Mutations to the gene result in amelogenesis imperfecta, hypomaturation type 2A6.