PIPA533828

mGluR7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533828-Each-of-1 In Stock ₹ 46,502.50

PIPA533828 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

mGluR7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRM7

Gene Alias

6330570A01Rik; BB176677; C030018L03; E130018M02Rik; FLJ40498; G protein-coupled receptor GRM7; G protein-coupled receptor, family C, group 1, member G; GLUR7; glutamate metabotropic receptor 7; glutamate receptor; glutamate receptor, metabotropic 7; Gpr1g; Gprc1g; GRM7; Metabotropic glutamate receptor 7; metabotropic glutamate receptor mGluR7; metabotropic glutamate receptor subtype 7b; MGLU7; mGlu7a receptor; MGLUR7; PPP1R87; protein phosphatase 1, regulatory subunit 87

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100052696, 108073, 2917, 416112, 484674, 535362, 81672

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P35400, Q14831, Q68ED2

Gene Symbols

GRM7

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GRM7 / MGLUR7.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Description L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors
  • Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions
  • The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties
  • Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C
  • Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8
  • Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities
  • Multiple transcript variants encoding different isoforms have been found for this gene.