mGluR8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA533830-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA533830 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
mGluR8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRM8
Gene Alias
A230002O04; FLJ41058; G protein coupled receptor, family C, group 1, member H; G protein-coupled receptor family C group 1 member H; G protein-coupled receptor, family C, group 1, member H; GLUR8; glutamate metabotropic receptor 8; glutamate receptor; glutamate receptor, metabotropic 8; Gprc1h; Grm8; M mGlu8; Metabotropic glutamate receptor 8; metabotropic glutamate receptor subtype 8b; MGC126724; mGlu8; mGlur; mGluR8; mGluR8b
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100071655, 100344818, 100758817, 101108742, 14823, 2918, 427853, 482270
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
O00222, P47743
Gene Symbols
GRM8
Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GRM8 / MGLUR8.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human Primate, Ovine, Rabbit
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors
- Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions
- The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties
- Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C
- Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8
- Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.