PIPA533943

MRGD Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA533943-Each-of-1 In Stock ₹ 46,502.50

PIPA533943 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MRGD

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MRGPRD

Gene Alias

Beta-alanine receptor; G protein-coupled receptor MrgD; Gm499; G-protein coupled receptor TGR7; MAS related GPR family member D; mas-related G protein-coupled MRGD; Mas-related G protein-coupled receptor d; MAS-related gene D; MAS-related GPR, member D; mas-related G-protein coupled receptor member D; MAS-related G-protein coupled receptor, member D; Mgrd; MrgD; MRGD G protein-coupled receptor; MRGPRD; TGR7

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116512

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

Q8TDS7

Gene Symbols

MRGPRD

Immunogen

Synthetic 18 amino acid peptide from 4th cytoplasmic domain of human MRGPRD.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Percent identity with other species by BLAST analysis: Human (100%) Gorilla (94%) Gibbon (89%)
  • May regulate nociceptor function and/or development, including the sensation or modulation of pain
  • Functions as a specific membrane receptor for beta-alanine
  • Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor
  • Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i)
  • Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.