PIPA534159

RORA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA534159-Each-of-1 In Stock ₹ 46,502.50

PIPA534159 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

RORA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RORA

Gene Alias

9530021D13Rik; nmf267; NR1F1; Nuclear receptor ROR-alpha; nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR related orphan receptor A; RAR-related orphan receptor A; RAR-related orphan receptor alpha; retinoic acid receptor-related orphan receptor alpha; retinoid-related orphan receptor alpha; retinoid-related orphan receptor-alpha; ROR Alpha; ROR1; ROR2; ROR3; Rora; Roralpha; ROR-alpha; RORalpha1; RZRA; RZR-ALPHA; sg; staggerer; thyroid hormone nuclear receptor alpha variant 4; tmgc26; transcription factor RZR-alpha

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100147460, 100156637, 100357159, 19883, 300807, 535597, 6095

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P35398, P51448

Gene Symbols

RORA

Immunogen

Synthetic 20 amino acid peptide from ligand-binding domain of human ROR Alpha.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Bovine, Equine, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • RORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain
  • RORA binds either as a monomer or as a homodimer to the retinoic acid response element and thus regulates gene expression and also controls cell function
  • Though the exact function of RORA is yet unknown, it interacts with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, NM23-1, the product of a tumor metastasis suppressor candidate gene, CDK7, NCOA3 and NCOA6 coactivators
  • It is found to express in mesenchymal stem cells derived from bone marrow and are known to act by direct modulation of a bone matrix component
  • It is widely expressed in most of the tissues
  • Chromosomal aberrations involving RORA may be a cause of acute promyelocytic leukemia (APL).