PIPA534162

RORB Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA534162-Each-of-1 In Stock ₹ 46,591.50

PIPA534162 - Each of 1

₹ 46,591.50

In Stock

Quantity

1

Base Price: ₹ 46,591.50

GST (18%): ₹ 8,386.47

Total Price: ₹ 54,977.97

Antigen

RORB

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RORB

Gene Alias

bA133M9.1; Nr1f2; Nuclear receptor ROR-beta; nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; RAR related orphan receptor B; RAR-related orphan receptor B; RAR-related orphan receptor beta; retinoic acid-binding receptor beta; retinoid-related orphan receptor b; retinoid-related orphan receptor beta; retinoid-related orphan receptor-beta; ror beta; Rorb; Rorbeta; ROR-BETA; rzrb; RZR-beta; sb:eu943; transcription factor; Unknown (protein for IMAGE:7173671)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100049831, 100169935, 100345295, 100771338, 225998, 309288, 395980, 484164, 6096

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P45446, Q8R1B8, Q92753

Gene Symbols

RORB

Immunogen

Synthetic 18 amino acid peptide from hinge domain of human ROR Beta.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human Primate, Ovine, Rabbit, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing
  • Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility
  • ROR beta binds to the monomeric response elements containing the sequence AnnTAGGTCA as a monomer
  • An alternatively spliced isoform, ROR beta2, has been isolated from rats, and the expression of ROR beta2 is confined to the pineal gland and retina
  • ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but is characterized by a different amino-terminal domain
  • ROR beta expression has been documented in various regions of the mouse brain.