PC4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA551557-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA551557 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
PC4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Sub1
Gene Alias
activated RNA polymerase II transcription cofactor 4; activated RNA polymerase II transcriptional coactivator p15; AI842364; hypothetical protein LOC553561; p14; P15; P9; Pc4; positive cofactor 4; pR-ET2 encoded oncodevelopmental protein; RNA polymerase II transcriptional coactivator; Rpo2tc1; Single-stranded DNA-binding protein p9; Sub1; SUB1 homolog; SUB1 homolog (S. cerevisiae); SUB1 homolog a; SUB1 homolog, transcriptional regulator; SUB1 homolog, transcriptional regulator a; SUB1 regulator of transcription; SUB1 regulator of transcription a; sub1a; TIS7; zgc:109973
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10923
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.02 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P53999
Gene Symbols
Sub1
Immunogen
Recombinant protein corresponding to Human PC4
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: VSSSSSGSDS DSEVDKKLKR KKQVAPEKPV KKQKTGETSR ALSSSKQSSS SRDDNMFQIG KMRYVSVRDF KGKVLIDIRE YWMDPEGEMK PGRKGISLNP EQWSQLKEQI Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%
- PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity
- The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH
- TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.