PIPA551926

IVNS1ABP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA551926-Each-of-1 In Stock ₹ 52,243.00

PIPA551926 - Each of 1

₹ 52,243.00

In Stock

Quantity

1

Base Price: ₹ 52,243.00

GST (18%): ₹ 9,403.74

Total Price: ₹ 61,646.74

Antigen

IVNS1ABP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IVNS1ABP

Gene Alias

1190004M08Rik; 1700126I16Rik; AA960440; ARA3; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3; FLARA3; HSPC068; influenza virus NS1A binding protein; influenza virus NS1A-binding protein; Influenza virus NS1A-binding protein homolog; Ivns1abp; kelch family protein Nd1; kelch family protein Nd1-L; kelch-like family member 39; Kelch-like protein 39; KIAA0850; KLHL39; mKIAA0850; NCX downstream gene 1; ND1; Nd1L; Nd1-L; ND1-L2; Nd1S; Nd1-S; NS1; NS-1; NS1-binding protein; NS1-binding protein homolog; Ns1bp; NS1-BP

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10625

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9Y6Y0

Gene Symbols

IVNS1ABP

Immunogen

Recombinant protein corresponding to Human IVNS1ABP

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: QDELIEKPMS PMQYARSGLG TAEMNGKLIA AGGYNREECL RTVECYNPHT DHWSFLAPMR TPRARFQMAV LMGQLYVVGG SNGHSDDLSC GEMYDSNIDD WIPVPELRTN RCNAGVCALN GKLYIVGGSD Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%
  • IVNS1ABP is a protein coding gene involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination
  • Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats
  • Protects cells from cell death induced by actin destabilization
  • Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription
  • In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors
  • Inhibits pre-mRNA splicing (in vitro).; (Microbial infection) involved in the alternative splicing of influenza A virus M1 mRNA through interaction with HNRNPK, thereby facilitating the generation of viral M2 protein.