PHC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA552370-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA552370 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
PHC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PHC1
Gene Alias
AW557034; DKFZp686A1782; early development regulator 1 (homolog of polyhomeotic 1); early development regulator1 (homolog of polyhomeotic 1); early development regulatory protein 1; Edr; Edr1; hPH1; MCPH11; Mph1; PH1; Phc1; polyhomeotic homolog 1; polyhomeotic homolog 1 (Drosophila); polyhomeotic-like 1; polyhomeotic-like 1 (Drosophila); polyhomeotic-like protein 1; RAE28; RAE-28
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1911
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P78364
Gene Symbols
PHC1
Immunogen
Recombinant protein corresponding to Human PHC1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LNQSQAQMYL RPQLGNLLQV NRTLGRNVPL ASQLILMPNG AVAAVQQEVP SAQSPGVHAD ADQVQNLAVR NQQASAQGPQ MQGS Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 96%
- Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development
- PHC1 (polyhomeotic homolog 1), also known as EDR1, HPH1 or RAE28, is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex
- Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A
- Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others
- Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain
- PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.