TRAF5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA552507-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA552507 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
TRAF5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TRAF5
Gene Alias
2700049M22Rik; AI875481; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; BID; MGC:39780; p11 BID; p13 BID; p15 BID; p22 BID; RING finger protein 84; RNF84; TNF receptor associated factor 5; TNF receptor-associated factor 5; Traf5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7188
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O00463
Gene Symbols
TRAF5
Immunogen
Recombinant protein corresponding to Human TRAF5
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: NAKVILGRYQ QDHLQQCLFQ PVQCSNEKCR EPVLRKDLKE HLSASCQFRK EKCLYCKKDV VVINLQNHEE NLCPEYPVFC PNNCAKIILK TEVDEHLAVC PEAEQDCPFK HYGCAVTDKR Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 69%
- Tumor necrosis factor (TNF) induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins, such as TNF receptor associated proteins (TRAFs)
- TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e
- g
- RANK, CD30, CD40, etc
- ) and the interleukin-1 receptor
- The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization
- Recent molecular cloning studies have lead to identification of six TRAFs (TRAF1-TRAF6) (1-4)
- TRAF5 is a 558-amino acid protein
- TRAF5 is implicated in NF-kB and c-Jun NH(2)-terminal kinase/stress-activated protein kinase activation by members of the TNF receptor superfamily, including CD27, CD30, CD40, and lymphotoxin-beta receptor
- Targeted disruption of TRAF5 gene causes defects in CD40-CD27 mediated lymphocyte activation (5).