PIPA553748

HHATL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA553748-Each-of-1 In Stock ₹ 52,332.00

PIPA553748 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

HHATL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HHATL

Gene Alias

1110011D13Rik; C3orf3; Glycerol uptake/transporter homolog; GUP1; GUP1 glycerol uptake/transporter homolog; Gup1, glycerol uptake/transporter homolog; hedgehog acyltransferase-like; hedgehog acyltransferase-like protein; HHATL; KIAA1173; MBOAT3; membrane bound O-acyltransferase domain containing 3; MSTP002; OACT3; Protein-cysteine N-palmitoyltransferase HHAT-like protein; RGD1311911

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57467

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

Lot-Specific

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9HCP6

Gene Symbols

HHATL

Immunogen

Recombinant protein corresponding to Human HHATL

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: ASFKMDPLIS WQSGFVTGTF DLQEVLFHGG SSFTVLRCTS FALESCAHPD RHYSLADLLK YNFYLPFFFF GPIMTFDRFH AQVSQVEPVR REGELWHIRA Q Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 90%
  • The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S
  • cerevisiae Gup1
  • It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH
  • HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development.