PIPA584746

Munc13-4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA584746-Each-of-1 In Stock ₹ 52,332.00

PIPA584746 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

Munc13-4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Unc13d

Gene Alias

2610108D09Rik; FHL3; HLH3; HPLH3; Jinx; likely ortholog of H. sapiens unc-13 homolog D (UNC13D); mFLJ00067; munc 13-4; Munc13-4; Protein unc-13 homolog D; unc-13 homolog D; unc-13 homolog D (C. elegans); Unc13d

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

201294

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q70J99

Gene Symbols

Unc13d

Immunogen

Recombinant protein corresponding to Human UNC13D

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SFHLDMWDLD TVESVRQKLG ELTDLHGLRR IFKEARKDKG QDDFLGNVVL RLQDLRCRED QWYPLEPRTE TYPDRGQCHL QFQLIHKRRA TSASRSQPSY TVHLHLLQQL VSHEVTQHEA GSTSWDGSLS PQAATVLFLH ATQKDLSD This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins
  • The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion
  • Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.