Septin 2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA553814-Each-of-1 | In Stock | ₹ 52,065.00 |
PIPA553814 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,065.00
GST (18%): ₹ 9,371.70
Total Price: ₹ 61,436.70
Antigen
Septin 2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SEPTIN2
Gene Alias
2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; Sept2; septin 2; Septin2; septin-2; Vascular endothelial cell specific protein 11; Vesp11
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
117515, 18000, 4735
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P42208, Q15019, Q91Y81
Gene Symbols
SEPTIN2
Immunogen
Recombinant protein corresponding to Human Septin 2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: WGVVEVENPE HNDFLKLRTM LITHMQDLQE VTQDLHYENF RSERLKRGGR KVENEDMNKD QILLEKEAEL RRMQEMIARM QAQMQMQMQG GDGDGGALGH Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%
- Septin 2 is a filament-forming cytoskeletal GTPase
- Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin
- It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression
- During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation
- Septin 2 also plays a role in ciliogenesis and collective cell movements.