PIPA554016

ELAC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA554016-Each-of-1 In Stock ₹ 48,905.50

PIPA554016 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

ELAC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Elac2

Gene Alias

1110017O07Rik; COXPD17; D11Wsu80e; elaC homolog 2; elaC homolog 2 (E. coli); elaC homolog protein 2; elaC ribonuclease Z 2; ELAC2; elaC-like protein 2; ELC2; heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; tRNase Z(L); zinc phosphodiesterase ELAC protein 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

60528

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

Lot-Specific

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9BQ52

Gene Symbols

Elac2

Immunogen

Recombinant protein corresponding to Human ELAC2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: WMERFGPDTQ HLVLNENCAS VHNLRSHKIQ TQLNLIHPDI FPLLTSFRCK KEGPTLSVPM VQGECLLKYQ LRPRREWQRD AIITCNPEEF IVEALQLPNF QQSVQEYR Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%
  • ELAC2 encodes a protein that has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs
  • The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest
  • Mutations in this gene result in an increased risk of prostate cancer
  • Multiple transcript variants encoding different isoforms have been found for this gene.