AKAP13 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA554078-Each-of-1 | In Stock | ₹ 49,172.50 |
PIPA554078 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,172.50
GST (18%): ₹ 8,851.05
Total Price: ₹ 58,023.55
Antigen
AKAP13
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AKAP13
Gene Alias
1700026G02Rik; 5730522G15Rik; 5830460E08Rik; A kinase (PRKA) anchor protein 13; AKAP13; AKAP-13; AKAP-Lbc; A-kinase anchor protein 13; A-kinase anchoring protein; A-kinase anchoring protein 13; ARHGEF13; Breast cancer nuclear receptor-binding auxiliary protein; Brx; c-lbc; guanine nucleotide exchange factor Lbc; HA-3; Ht31; Human thyroid-anchoring protein 31; LBC; LBC oncogene; lymphoid blast crisis oncogene; Non-oncogenic Rho GTPase-specific GTP exchange factor; p47; PRKA13; Protein kinase A-anchoring protein 13; PROTO-LB; PROTO-LBC; type II cAMP-dependent protein kinase anchoring protein Ht31
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11214
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.3 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q12802
Gene Symbols
AKAP13
Immunogen
Recombinant protein corresponding to Human AKAP13
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: ARELKEQLHQ KDQKILLLLE EKEMIFRDMA ECSTPLPEDC SPTHSPRVLF RSNTEEALKG GPLMKSAINE VEILQGLVSG NLGGTLGPTV SSPIEQDVVG PVSLPR Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%
- The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell
- This gene encodes a member of the AKAP family
- Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains
- The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals
- The PH domain has multiple functions
- Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta.