PIPA554234

ASZ1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA554234-Each-of-1 In Stock ₹ 52,065.00

PIPA554234 - Each of 1

₹ 52,065.00

In Stock

Quantity

1

Base Price: ₹ 52,065.00

GST (18%): ₹ 9,371.70

Total Price: ₹ 61,436.70

Antigen

ASZ1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Asz1

Gene Alias

4933400N19Rik; ALP1; ANKL1; ankyrin repeat, SAM and basic leucine zipper domain containing 1; ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; ankyrin-like 1; ankyrin-like protein 1; Asz1; C7orf7; CT1.19; GASZ; germ cell-specific ankyrin, SAM and basic leucine zipper domain containing protein; germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein; Orf3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

136991

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8WWH4

Gene Symbols

Asz1

Immunogen

Recombinant protein corresponding to Human ALP1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: DGHTQVVALL VAHGAEVNTQ DENGYTALTW AARQGHKNIV LKLLELGANK MLQTKDGKMP SEIAKRNKHH EIFNLLSFTL NPLEGKLQQL TKED Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%
  • Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity
  • Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons
  • Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process
  • Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons
  • May act by mediating protein-protein interactions during germ cell maturation.