PIPA554095

SSH1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA554095-Each-of-1 In Stock ₹ 48,905.50

PIPA554095 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

SSH1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SSH1

Gene Alias

hSSH-1L; KIAA1298; Protein phosphatase Slingshot homolog 1; slingshot homolog 1; slingshot protein phosphatase 1; SSH1; SSH1L; SSH-1L; SSH-like protein 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54434

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8WYL5

Gene Symbols

SSH1

Immunogen

Recombinant protein corresponding to Human SSH1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LCEKDVKKKL EFGSPKGRSG SLLQVEETER EEGLGAGRWG QLPTQLDQNL LNSENLNNNS KRSCPNGMED DAIFGILNKV KPSYKSCADC MYPTASGAPE ASRERCEDPN APAICTQPAF LPHITSSPVA HLASRS Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 69%
  • This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes
  • The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin
  • It possesses at least two conserved domains that could be important for its function
  • First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus
  • Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation
  • It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions
  • Two transcript variants encoding different isoforms have been found for this gene.