PIPA554239

BAG3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA554239-Each-of-1 In Stock ₹ 49,439.50

PIPA554239 - Each of 1

₹ 49,439.50

In Stock

Quantity

1

Base Price: ₹ 49,439.50

GST (18%): ₹ 8,899.11

Total Price: ₹ 58,338.61

Antigen

BAG3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BAG3

Gene Alias

AA407278; BAG family molecular chaperone regulator 3; BAG3; BAG-3; BCL2 associated athanogene 3; Bcl-2-associated athanogene 3; Bcl2-associated athanogene 3; BCL2-binding athanogene 3; bcl-2-binding protein Bis; Bcl-2-interacting death suppressor; BIS; CAIR-1; DKFZp434E0610; docking protein CAIR-1; MFM6; mg638; MGC104307; MNCb-2243

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9531

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O95817

Gene Symbols

BAG3

Immunogen

Recombinant protein corresponding to Human BAG3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: DCSSSSSSAS LPSSGRSSLG SHQLPRGYIS IPVIHEQNVT RPAAQPSFHQ AQKTHYPAQQ GEYQTHQPVY HKIQGDDWEP RPLRAASPFR SSVQGASSRE GSPARSSTPL HSPSPIRVHT VVDRPQQPMT HRET Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%
  • BAG3 are among BAG proteins that compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release
  • All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions
  • The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region
  • The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells
  • All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.