HPD Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA558342-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA558342 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
HPD
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Hpd
Gene Alias
4H GLOD3; 4-H HPPDASE; 4HPPD; 4-HPPD; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; f Alloantigen; F liver antigen; f protein; Fla; Flp; GLOD3; glyoxalase domain containing 3; HPD; Hppd; HPPDASE; Laf; PPD
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3242
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P32754
Gene Symbols
Hpd
Immunogen
Recombinant protein corresponding to Human HPD
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MTTYSDKGAK PERGRFLHFH SVTFWVGNAK QATSFYCSKM GFEPLAYRGL ETGSREVVSH VIKQGKIVFV LSSALNPWNK EMGDHLVKHG DG Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%
- The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli
- All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3)
- Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli
- This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4)
- Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus
- The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.