WDR35 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560629-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA560629 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
WDR35
Classification
Polyclonal
Conjugate
Unconjugated
Gene
WDR35
Gene Alias
4930459M12Rik; 4931430C06; CED2; IFT121; IFTA1; intraflagellar transport protein 121 homolog; KIAA1336; mKIAA1336; Naofen; RGD1564116; SRTD7; WD repeat domain 35; WD repeat domain 35-like; WD repeat-containing protein 35; WDR35; Wdr35l
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57539
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.05 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9P2L0
Gene Symbols
WDR35
Immunogen
Recombinant protein corresponding to Human WDR35
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SLPNVGLIQK YSLNCRAYQL SLNCNSSRLA IIDISGVLTF FDLDARVTDS TGQQVVGELL KLERRDVWDM KWAKDNPDLF AMMEKTRMYV FRNLDPEEPI QTSGY Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%
- WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription
- One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities
- WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia
- Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.