STIM1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582412-Each-of-1 | In Stock | ₹ 53,400.00 |
PIPA582412 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,400.00
GST (18%): ₹ 9,612.00
Total Price: ₹ 63,012.00
Antigen
STIM1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STIM1
Gene Alias
D11S4896E; GOK; IMD10; RGD:1306831}; SIM; Stim1; stim1 {ECO:0000312; STIM1L; STRMK; Stromal interaction molecule 1; stromal interaction molecule 1 precursor; TAM; TAM1
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6786
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q13586
Gene Symbols
STIM1
Immunogen
Recombinant protein corresponding to Human STIM1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TAKQALSEVT AALRERLHRW QQIEILCGFQ IVNNPGIHSL VAALNIDPSW MGSTRPNPAH FIMTDDVDDM DEEIVSPLSM QSPSLQSSVR QRLTEPQHGL GSQRDLTHSD SESSLHMSDR QRVAPKPPQM SRAADEALNA MTSNGSH STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane
- Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm
- However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet
- Many questions also remain to be solved around STIM1 functional distribution
- It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.