HINT1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560760-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA560760 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
HINT1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Hint1
Gene Alias
17 kDa inhibitor of protein kinase C; AA673479; Adenosine 5'-monophosphoramidase; FLJ30414; FLJ32340; HINT; Hint1; histidine triad nucleotide binding protein 1; histidine triad nucleotide-binding protein 1; Ipk1; NMAN; PKC inhibitor/ interacting protein; Pkci; PKCI1; PKCI-1; Prkci; PRKCNH1; protein kinase C inhibitor 1; protein kinase C, iota; protein kinase C-interacting protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15254, 3094, 690660
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P49773, P62959, P70349
Gene Symbols
Hint1
Immunogen
Recombinant protein corresponding to Human HINT1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: IPKKHISQIS VAEDDDESLL GHLMIVGKKC AADLGLNKGY RMVVNEGSDG GQSVYHVHLH VL Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%
- Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins
- HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities
- HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression
- Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1
- Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.