HM13 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA560919-Each-of-1 | In Stock | ₹ 42,319.50 |
PIPA560919 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,319.50
GST (18%): ₹ 7,617.51
Total Price: ₹ 49,937.01
Antigen
HM13
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HM13
Gene Alias
1200006O09Rik; 4930443L17Rik; 5031424B04Rik; AV020344; cb228; H13; H-13; hIMP1; histocompatibility (minor) 13; histocompatibility 13; histocompatibility minor 13; HM13; hm13 protein; IMP1; IMP-1; IMPAS; IMPAS-1; intramembrane aspartyl protease; intramembrane protease 1; minor histocompatibility antigen 13; minor histocompatibility antigen H13; MSTP086; presenilin-like aspartyl protease; presenilin-like protein 3; PSENL3; PSL3; Signal peptide peptidase; signal peptide peptidase beta; signal peptide peptidase like 1; SPP; SPPL1; Unknown (protein for MGC:134054); wu:fc11a06; zgc:56660; zgc:86862
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
81502
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.10 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q8TCT9
Gene Symbols
HM13
Immunogen
Recombinant protein corresponding to Human HM13
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: PASFPNRQYQ LLFTQGSGEN KEEIINYEFD TKDLVCLGLS SIVGVWYLLR KHWIANNLFG LAFSLNGVEL LHLNNVSTGC Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%
- Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm
- Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides
- May play a role in graft rejection
- May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein
- Involved in the intramembrane cleavage of the integral membrane protein PSEN1
- Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139- dependent manner.