PIPA566506

ATXN1L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA566506-Each-of-1 In Stock ₹ 48,905.50

PIPA566506 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

ATXN1L

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATXN1L

Gene Alias

ankyrin repeat and SOCS box containing 16; ankyrin repeat and SOCS box protein 16; ankyrin repeat and SOCS box-containing 16; ankyrin repeat and SOCS box-containing protein 16; ASB16; ASB-16; ataxin 1 like; ataxin 1-like; ataxin-1-like; ATXN1L; BOAT; BOAT1; Brother of ataxin-1; brother of ATXN1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

342371

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P0C7T5

Gene Symbols

ATXN1L

Immunogen

Recombinant Human ATXN1L

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: AHSFNKAPSAT SPSGQLPHHS STQPLDLAPG RMPIYYQMSR LPAGYTLHET PPAGASPVLT PQESQS Highest antigen sequence identity to the following orthologs - mouse 87%, rat 84%
  • Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor
  • Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (PubMed:21475249)
  • Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1)
  • In concert with CIC and ATXN1, involved in brain development
  • [UniProt]