ADAM23 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA568083-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA568083 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
ADAM23
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ADAM23
Gene Alias
a disintegrin and metallopeptidase domain 23; a disintegrin and metalloprotease domain 23; a disintegrin and metalloproteinase; ADAM; ADAM 23; ADAM metallopeptidase domain 23; ADAM23; ADAM-23; ADAMs; AW046396; disintegrin and metalloproteinase domain-containing protein 23; MDC3; MDC-3; metalloendopeptidases; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3
Host Species
Rabbit
Purification Method
affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23792, 8745
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 30% glycerol and 0.01% sodium azide, pH 7.3
Gene Accession No.
O75077, Q9R1V7
Gene Symbols
ADAM23
Immunogen
Synthesized peptide derived from human ADAM23.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Predicted to react with Mouse samples
- ADAMs (a disintegrin and metalloproteinase domain), also known as MDCs (metalloproteinase, disintegrin, and cysteine-rich domain) or cellular disintegrins, are a family of proteins that are expressed in numerous different tissues
- They catalyze proteolysis, adhesion, fusion and intracellular signaling
- ADAMs are membrane-anchored proteins, and there are over 30 different members in the family with many diverse functions
- ADAM 23 is exclusively expressed in fetal and adult brain and may function as an integrin ligand in cells of neural origin
- Adhesion of neuroblastoma and astrocytoma cells is promoted by the disentegrin-like domain of ADAM23 and is mediated by an interaction of this protein with αvβ3
- A short amino acid sequence in the disintegrin loop of ADAM23 interacts with αvβ3 to mediate cell interactions that take place during both normal and pathological processes
- The three characteristic histidine residues and the glutamic acid residue typical of metalloproteinases are lacking in the metalloproteinase-like domain of ADAM23
- This suggests that ADAM23 may not be involved in protease-mediated events, but could exclusively serve in cell adhesion processes
- In addition, evidence suggests that ADAM23 may be a tumor suppressor gene.