APOBEC3H Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA568166-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA568166 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
APOBEC3H
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APOBEC3H
Gene Alias
A3H; APOBEC3H; APOBEC-related protein 10; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3H; apolipoprotein B mRNA editing enzyme catalytic subunit 3H; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H; ARP10; ARP-10; DNA dC->dU-editing enzyme APOBEC-3H
Host Species
Rabbit
Purification Method
affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
164668
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q6NTF7
Gene Symbols
APOBEC3H
Immunogen
Synthesized peptide derived from human APOBEC3H.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms
- The A3H-var/haplotype 2 exhibits antiviral activity against vif-deficient HIV-1
- After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA
- The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells
- Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA
- Exhibits antiviral activity also against T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons.