PIPA572953

Pyruvate Carboxylase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572953-Each-of-1 In Stock ₹ 46,146.50

PIPA572953 - Each of 1

₹ 46,146.50

In Stock

Quantity

1

Base Price: ₹ 46,146.50

GST (18%): ₹ 8,306.37

Total Price: ₹ 54,452.87

Antigen

Pyruvate Carboxylase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PC

Gene Alias

EC 6.4.1.1; Pc; Pcb; Pcx; PYC; pyruvate carboxylase; pyruvate carboxylase, mitochondrial; pyruvate decarboxylase; pyruvic carboxylase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18517, 18563, 25104, 5091

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P11498, P52873, Q05920

Gene Symbols

PC, Pcx

Immunogen

A genomic peptide made to an internal region of the human Pyruvate Carboxylase protein (within residues 930-1050). [Swiss-Prot P11498]

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate
  • The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix
  • Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate
  • Mutations in this gene have been associated with pyruvate carboxylase deficiency.