PIPA578100

Pyruvate Carboxylase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578100-Each-of-1 In Stock ₹ 48,905.50

PIPA578100 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

Pyruvate Carboxylase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PC

Gene Alias

EC 6.4.1.1; Pc; Pcb; Pcx; PYC; pyruvate carboxylase; pyruvate carboxylase, mitochondrial; pyruvate decarboxylase; pyruvic carboxylase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25104, 5091

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.69 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P11498, P52873

Gene Symbols

PC

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human Pyruvate Carboxylase. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Pig (97%), Chicken (84%), Rhesus Monkey (100%), Bovine (96%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Pyruvate Carboxylase requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate
  • The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix
  • Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate
  • Mutations in this gene have been associated with pyruvate carboxylase deficiency.