PIPA575378

HCCS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575378-Each-of-1 In Stock ₹ 46,502.50

PIPA575378 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

HCCS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HCCS

Gene Alias

CCHL; cytochrome c heme-lyase; cytochrome c-type heme lyase; HCCS; holocytochrome c synthase; holocytochrome c synthetase; holocytochrome c-type synthase; LSDMCA1; MCOPS7; microphthalamia with linear skin defects; MLS; RGD1563855

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15159, 3052, 317444

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide; pH 7.2

Gene Accession No.

P53701, P53702

Gene Symbols

HCCS

Immunogen

Synthetic peptide corresponding to amino acids 80-120 of Human HCCS.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • CCHL (cytochrome c-type heme lyase), also known as HCCS (holocytochrome c-type synthase), is a 268 amino acid mitochondrial inner membrane protein that belongs to the cytochrome c-type heme lyase family
  • Containing two HRM (heme regulatory motif) repeats, HCCS participates in the covalent linkage of a heme group to an apoprotein of cytochrome c
  • The gene encoding HCCS maps to the human X chromosome
  • Defects to this gene cause microphthalmia syndromic type 7 (MCOPS7), also known as MIDAS syndrome or microphthalmia with linear skin defects (MLS)
  • MCOPS7 is an X-linked male-lethal disorder that results in eye deformation, unilateral or bilateral microphthalmia, linear skin defects in affected females, and in utero lethality for males.