AVPR2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA575409-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA575409 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
AVPR2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AVPR2
Gene Alias
ADHR; antidiuretic hormone receptor; arginine vasopressin receptor 2; Avp2r; AVPR V2; AVPR2; DI1; DIR; DIR3; MGC126533; MGC138386; ND1; NDI; nephrogenic diabetes insipidus; renal-type arginine vasopressin receptor; V2R; V2-renal V2R; Vasopressin receptor V2; vasopressin V2 receptor; VPV2R
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12000, 25108, 554
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O88721, P30518, Q00788
Gene Symbols
AVPR2
Immunogen
Synthetic peptide corresponding to amino acids 80-130 of Human AVPR2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
- Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin
- Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus
- Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream
- The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary
- Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems
- Avpr2 has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels
- Avpr2 can contract smooth muscle during parturition and lactation
- Avpr2 is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions
- The activity of Avpr2 is mediated by G proteins which activate adenylate cyclase.