AVEN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582735-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA582735 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
AVEN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AVEN
Gene Alias
1700013A01Rik; 1700056A21Rik; apoptosis and caspase activation inhibitor; apoptosis, caspase activation inhibitor; AVEN; Cell death regulator Aven; mAven-L; mAven-S; PDCD12; programmed cell death 12
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57099
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9NQS1
Gene Symbols
AVEN
Immunogen
Recombinant protein corresponding to Human AVEN
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: GPSRDSQKPT SPLQSAGDHL EEELDLLLNL DAPIKEGDNI LPDQTSQDLK SKEDGEVVQE EEVCAKPSVT EEKNMEPEQP STSK Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells
- Disruption of this process has been implicated in a variety of diseases such as cancer
- Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9
- It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation
- Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients.