Aconitase 1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA577845-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA577845 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
Aconitase 1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ACO1
Gene Alias
ACO1; Aco-1; Acon1; Aconitase; aconitase 1; aconitase 1, soluble; aconitate hydratase, cytoplasmic; ACONS; AH; Citrate hydro-lyase; cytoplasmic aconitase; cytoplasmic aconitate hydratase; cytosplasmic aconitase; epididymis luminal protein 60; ferritin repressor protein; FRP; HEL60; Ireb1; Irebp; IRE-BP 1; IREBP1; iron regulatory protein 1; iron-responsive element binding protein 1; iron-responsive element-binding protein 1; IRP1; OTTHUMP00000021176; OTTHUMP00000021177; OTTHUMP00000045233; soluble aconitase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
48
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P21399
Gene Symbols
ACO1
Immunogen
Recombinant protein encompassing a sequence within the center region of human Aconitase 1. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: A431, HeLa, HepG2 Predicted Reactivity: Mouse (87%), Rat (86%), Rabbit (90%), Rhesus Monkey (99%), Bovine (89%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Aconitase 1 (ACO1) also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs)
- It plays a central role in cellular iron homeostasis
- It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs)
- IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA
- The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA
- Thus, IREB1 plays a central role in cellular iron homeostasis
- It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.