TRRAP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578246-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA578246 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
TRRAP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TRRAP
Gene Alias
350/400 kDa PCAF-associated factor; AI481500; OTTHUMP00000197294; OTTHUMP00000197295; PAF350/400; PAF400; STAF40; Tra1; Tra1 homolog; transactivation/transformation-domain associated protein; transformation/transcription domain associated protein; transformation/transcription domain-associated protein; TR-AP; TRRAP
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8295
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ChIP Assay, Immunoprecipitation, Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q9Y4A5
Gene Symbols
TRRAP
Immunogen
Recombinant protein encompassing a sequence within the center region of human TRRAP. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: Jurkat, Raji, NCI-H929, 293T, A431, HeLa, HepG2 Predicted Reactivity: Mouse (98%), Rat (98%), Japanese Medaka (89%), Bovine (100%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- TRRAP is an adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation
- Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A
- TRRAP plays a central role in MYC transcription activation, and also participates in cell transformation by MYC is required for p53/TP53-, E2F1- and E2F4-mediated transcription activation and is also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes
- TRRAP probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation, however, it is probably not required in the steps following histone acetylation in processes of transcription activation
- TRRAP may be required for the mitotic checkpoint and normal cell cycle progression
- TRRAP is a component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.