FADD Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578260-Each-of-1 | In Stock | ₹ 51,620.00 |
PIPA578260 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,620.00
GST (18%): ₹ 9,291.60
Total Price: ₹ 60,911.60
Antigen
FADD
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FADD
Gene Alias
Fadd; Fas (TNFRSF6)-associated via death domain; Fas associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associating protein with death domain; GIG3; Growth-inhibiting gene 3 protein; mediator of receptor induced toxicity; mediator of receptor-induced toxicity; MGC8528; MORT1; Mort1/FADD; protein FADD
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8772
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.58 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.
Q13158
Gene Symbols
FADD
Immunogen
Recombinant protein encompassing a sequence within the center region of Human FADD. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: HeLa, HeLa (30 μM Cisplatin treatment for 24 hr) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals
- Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors
- Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade
- Knockout studies in mice also suggest the importance of this protein in early T cell development.