PIPA578345

MMP24 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578345-Each-of-1 In Stock ₹ 48,994.50

PIPA578345 - Each of 1

₹ 48,994.50

In Stock

Quantity

1

Base Price: ₹ 48,994.50

GST (18%): ₹ 8,819.01

Total Price: ₹ 57,813.51

Antigen

MMP24

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MMP24

Gene Alias

AU040325; matrix metallo protease; matrix metallopeptidase 24; matrix metallopeptidase 24 (membrane-inserted); matrix metalloproteinase 24; matrix metalloproteinase 24 (membrane-inserted); matrix metalloproteinase-21; Matrix metalloproteinase-24; membrane type 5-MMP; membrane-type 5 matrix metalloproteinase; membrane-type matrix metalloproteinase 5; Membrane-type-5 matrix metalloproteinase; MMP; Mmp21; MMP-21; Mmp24; MMP-24; MMP25; MMPs; MT5MMP; Mt5-mmp; MT-MMP 5; MTMMP5; MT-MMP5; Processed matrix metalloproteinase-24; RP4-614O4.10

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10893, 17391

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9R0S2, Q9Y5R2

Gene Symbols

MMP24

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human MMP24. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: SK-N-SH, IMR32, human MMP24-transfected 293T, mouse brain Predicted Reactivity: Rat (83%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure
  • The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix
  • Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell-matrix interactions
  • MMPs are Zn (2+)-binding endopeptidases that degrade various components of the ECM
  • MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion
  • These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases)
  • TIMPs have been shown to block tumor cell invasion suggesting that they act as metastasis suppressor genes.