PIPA578484

BRD7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578484-Each-of-1 In Stock ₹ 48,905.50

PIPA578484 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

BRD7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BRD7

Gene Alias

75 kDa bromodomain protein; BP75; BRD7; bromodomain containing 7; bromodomain protein 75 kDa; bromodomain-containing 7; bromodomain-containing 7-like protein; bromodomain-containing protein 7; CELTIX1; NAG4; protein CELTIX-1; protein tyrosine phosphatase, non-receptor type 13 interacting protein; Ptpn13ip

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29117

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q9NPI1

Gene Symbols

BRD7

Immunogen

Recombinant protein encompassing a sequence within the center region of human BRD7. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: HeLa, HeLa nuclear extract Predicted Reactivity: Mouse (85%), Rat (84%), Bovine (88%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • BRD7 acts both as coactivator and as corepressor
  • For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity
  • In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation
  • BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.