PIPA582191

HRD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA582191-Each-of-1 In Stock ₹ 52,332.00

PIPA582191 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

HRD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SYVN1

Gene Alias

1200010C09Rik; AW211966; C85322; D530017H19Rik; DER3; E3 ubiquitin-protein ligase synoviolin; HMG-coA reductase degradation 1 homolog; Hrd1; HRD1 protein; KIAA1810; MGC40372; RGD1310488; RING-type E3 ubiquitin transferase synoviolin; Synovial apoptosis inhibitor 1; synovial apoptosis inhibitor 1, synoviolin; synoviolin 1; Syvn1

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

84447

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.1 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q86TM6

Gene Symbols

SYVN1

Immunogen

Recombinant protein corresponding to Human SYVN1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PAPGFPFPPP WMGMPLPPPF AFPPMPVPPA GFAGLTPEEL RALEGHERQH LEARLQSLRN IHTLLDAAML QINQYLTVLA SLGPPRPATS VNSTEETATT VVAAASSTSI PSSEATTPTP GASPPAPEME RPPAPESVGT HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress
  • Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum
  • HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle
  • It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects
  • HRD1 contains one ring-type zinc finger.