Amphiphysin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA582701-Each-of-1 | In Stock | ₹ 51,620.00 |
PIPA582701 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,620.00
GST (18%): ₹ 9,291.60
Total Price: ₹ 60,911.60
Antigen
Amphiphysin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Amph
Gene Alias
Amph; AMPH1; amphiphysin; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen); amphiphysin 1; amphiphysin I; HGNC:471
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
218038, 273
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P49418, Q7TQF7
Gene Symbols
Amph
Immunogen
Recombinant protein corresponding to Human AMPH
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: EKVIPSVVIE PASNHEEEGE NEITIGAEPK ETTEDAAPPG PTSETPELAT EQKPIQDPQP TPSAPAMGAA DQLASAREA Amphiphysins, members of the BAR (Bin-Amphiphysin-Rvsp) protein super family, play a key role in clathrin-mediated endocytosis of synaptic vesicles (SVs)
- All members of the BAR family share a highly conserved N-terminal BAR domain and a C-terminal Src homology (SH3) domain
- Two isoforms of amphiphysin have been identified and act in concert as a heterodimer
- Amphiphysins interact via its carboxy-terminal SH3 domain with dynamin, synaptojanin and clathrin
- These complexes are implicated in synaptic vesicle recycling at nerve terminal
- Amphiphysins were also identified as the dominant autoantigen in paraneoplastic Stiff-Man Syndrome.