PIPA582702

Amphiphysin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA582702-Each-of-1 In Stock ₹ 52,332.00

PIPA582702 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

Amphiphysin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Amph

Gene Alias

Amph; AMPH1; amphiphysin; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen); amphiphysin 1; amphiphysin I; HGNC:471

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

273

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.4 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P49418

Gene Symbols

Amph

Immunogen

Recombinant protein corresponding to Human AMPH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PGFLYKVETL HDFEAANSDE LTLQRGDVVL VVPSDSEADQ DAGWLVGVKE SDWLQYRDLA TYKGLFPENF TRRL Amphiphysins, members of the BAR (Bin-Amphiphysin-Rvsp) protein super family, play a key role in clathrin-mediated endocytosis of synaptic vesicles (SVs)
  • All members of the BAR family share a highly conserved N-terminal BAR domain and a C-terminal Src homology (SH3) domain
  • Two isoforms of amphiphysin have been identified and act in concert as a heterodimer
  • Amphiphysins interact via its carboxy-terminal SH3 domain with dynamin, synaptojanin and clathrin
  • These complexes are implicated in synaptic vesicle recycling at nerve terminal
  • Amphiphysins were also identified as the dominant autoantigen in paraneoplastic Stiff-Man Syndrome.