PIPA584490

POLR3D Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA584490-Each-of-1 In Stock ₹ 48,905.50

PIPA584490 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

POLR3D

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Polr3d

Gene Alias

2810426M17Rik, 44kDa, AI326118, AW489084, BN51, BN51 (BHK21) temperature sensitivity complementing, Bn51t, DNA-directed RNA polymerase III 47 kDa polypeptide, DNA-directed RNA polymerase III subunit C4, DNA-directed RNA polymerase III subunit D, DNA-directed RNA polymerase III subunit RPC4, HOX1C, Polr3d, polymerase (RNA) III (DNA directed) polypeptide D, polymerase (RNA) III (DNA directed) polypeptide D, 44kDa, polymerase (RNA) III subunit D, Protein BN51, RNA polymerase III 47 kDa subunit, RNA polymerase III subunit C4, RNA polymerase III subunit D, RPC4, RPC53, RPC53 homolog, temperature sensitive complementation, cell cycle specific, tsBN51, TSBN51

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

661

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot, Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P05423

Gene Symbols

Polr3d

Immunogen

Recombinant protein corresponding to Human POLR3D

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: DRQREGHGRG RGRPEVIQSH SIFEQGPAEM MKKKGNWDKT VDVSDMGPSH IINIKKEKRE TDEE This gene encodes a protein which interacts with the N-terminal region of BRCA1
  • In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain
  • The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes
  • This protein also contains 3 tandem ankyrin repeats
  • The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression
  • This protein may be the target of oncogenic mutations in breast or ovarian cancer.