PIPA584656

Importin 4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA584656-Each-of-1 In Stock ₹ 48,905.50

PIPA584656 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

Importin 4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ipo4

Gene Alias

8430408O15Rik, AA409693, Imp4, Imp4a, IMP4B, importin 4, importin 4a, importin-4, Importin-4a, importin-4b, IPO4, Ran-binding protein 4, ranBP4

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

79711

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot, Western Blot

Concentration

0.4 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

Q8TEX9

Gene Symbols

Ipo4

Immunogen

Recombinant protein corresponding to Human IPO4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VRDNICGALA RLLMASPTRK PEPQVLAALL HALPLKEDLE EWVTIGRLFS FLYQSSPDQV IDVAPELLRI CSLILADNKI PPD Importin-4 is a protein that in humans is encoded by the IPO4 gene
  • Functions in nuclear protein import as nuclear transport receptor
  • Serves as receptor for nuclear localization signals (NLS) in cargo substrates
  • Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism
  • At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.